Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies
نویسندگان
چکیده
The development and use of combination immunotherapy-based anticancer regimens is at an early but clearly exciting stage. We now demonstrate that the antibody-based co-targeting of multiple immunostimulatory and/or inhibitory pathways can be used safely and effectively in combination with single dose or fractionated radiotherapy to cure mice bearing established mammary tumors.
منابع مشابه
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2012